How old antibiotic compounds could become tomorrow's life-saving drugs
As the fight against drug-resistant infections continues, University of Leeds scientists are looking back at previously discarded chemical compounds, to see if any could be developed for new antibiotics. In the heyday of antibiotic development in the mid-20th century many different chemical compounds with antibacterial properties were examined, but only a small proportion were selected for development into drugs.
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Drug trial protocol redactions by industry sponsors exposed
New research published by the Journal of the Royal Society of Medicine exposes the extent of redactions in protocols for industry-sponsored randomised drug trials. Trial protocols are needed for a proper assessment of the veracity of drug trial reports. The researchers, from the Nordic Cochrane Centre in Copenhagen, found widespread redactions in the protocols for commercially sponsored trials they received from research ethics committees in Denmark.
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AI 'scientist' finds that toothpaste ingredient may help fight drug-resistant malaria
An ingredient commonly found in toothpaste could be employed as an anti-malarial drug against strains of malaria parasite that have grown resistant to one of the currently-used drugs. This discovery, led by researchers at the University of Cambridge, was aided by Eve, an artificially-intelligent 'robot scientist'.
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Researchers develop a remote-controlled cancer immunotherapy system
A team of researchers has developed an ultrasound-based system that can non-invasively and remotely control genetic processes in live immune T cells so that they recognize and kill cancer cells. There is a critical need to non-invasively and remotely manipulate cells at a distance, particularly for translational applications in animals and humans, researchers said.
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A more complete Mediterranean diet may protect against aggressive prostate cancer
In a new study published in The Journal of Urology®, researchers determined that men who followed a Mediterranean diet, rich in fish, boiled potatoes, whole fruits, vegetables, legumes, and olive oil, and low consumption of juices had lower risk of aggressive prostate cancer (PC) than those who followed other dietary patterns like Prudent or Western diets.
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Cancer cells can be destroyed more effectively and selectively with a unique new reusable treatment
Led by Professor Peter J. Sadler from Warwick's Department of Chemistry, researchers have developed a new line of attack against cancer: an organic-osmium compound, which is triggered using a non-toxic dose of sodium formate, a natural product found in many organisms, including nettles and ants.
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Diabetes drug 'significantly reverses memory loss' in mice with Alzheimer's
A drug developed for diabetes could be used to treat Alzheimer's after scientists found it "significantly reversed memory loss" in mice through a triple method of action. The research, published in Brain Research, could bring substantial improvements in the treatment of Alzheimer's disease through the use of a drug originally created to treat type 2 diabetes.
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