Research

Leukemia, lymphoma squarely in sights of new class of drugs

UT Health San Antonio researchers, working with collaborators at the University of Florida, have discovered a safe and potent next generation of drugs to fight multiple types of leukemia and lymphoma in adults and children. The journal Nature Medicine reported the findings Dec. 2.

Olaparib becomes first gene-targeted medicine to show benefits in prostate cancer

A pioneering precision medicine already licensed for breast and ovarian cancer can also slow or stop tumour growth in some men with advanced prostate cancer, a new clinical trial shows. The phase II trial found that over 80 per cent of men with prostate cancer whose tumours had mutations in the BRCA genes responded well to treatment with the targeted drug olaparib.

The gut may be involved in the development of multiple sclerosis

It is incompletely understood which factors in patients with multiple sclerosis (MS) act as a trigger for the immune system to attack the brain and spinal cord. A potential factor is described by a research team in the journal Proceedings of the National Academy of Sciences, PNAS. The medical researchers used an animal model to show that the protein Smad7 mobilises immune cells in the intestines which, in turn, trigger inflammation in the central nervous system.

Investigational drugs reduce risk of death from Ebola virus disease

The investigational therapeutics mAb114 and REGN-EB3 offer patients a greater chance of surviving Ebola virus disease (EVD) compared to the investigational treatment ZMapp, according to published results from a clinical trial conducted in the Democratic Republic of the Congo (DRC). The new report also shows that early diagnosis and treatment are associated with an increased likelihood of survival from EVD.

Pharmacist-led interventions may help prevent cardiovascular disease

With their expertise in the safe and effective use of medications, pharmacists can help in the management of chronic diseases. A review and analysis published in the British Journal of Clinical Pharmacology indicates that initiatives - such as patient education, medication review, and physical assessments - led by pharmacists can make important contributions to the prevention of cardiovascular disease.

A protein tag to study the immune system

Researchers from VIB-UGent Center for Medical Biotechnology, University of Iowa (USA) and other collaborators, developed a novel approach to better understand a basic defense mechanism of our immune system. Central is ISG15, a small protein with a role in the immune system. With the newly developed method, scientists can now identify and study proteins tagged with ISG15, allowing them to

Excellent market conditions at largest ever CPhI Worldwide bodes well for global pharma in 2020

5 - 7 November 2019, Frankfurt, Germany.
CPhI Worldwide closed its doors on its landmark 30th edition at the Messe Frankfurt, with pre-audit figures showcasing a record total attendance of 48,961 - 84% of which were international. This year's event saw a number of key indicators pointing to a strong year ahead for pharma in 2020. CPhI Worldwide is widely recognised as a barometer of pharma's overall health - with the addition of

Research & Development

Leukemia, lymphoma squarely in sights of new class of drugs

Olaparib becomes first gene-targeted medicine to show benefits in prostate cancer

The gut may be involved in the development of multiple sclerosis

Investigational drugs reduce risk of death from Ebola virus disease

Pharmacist-led interventions may help prevent cardiovascular disease

A protein tag to study the immune system

Excellent market conditions at largest ever CPhI Worldwide bodes well for global pharma in 2020

More Pharma News ...